1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, decahydro-4-(2-propen-1-yl)-, (1S,4S,5S,11aR)- - Names and Identifiers
Name | angustifoline
|
Synonyms | Jamaicensine angustifoline (-)-Angustifoline Mixture of (-)-Angustifoline and Isoangustifoline (1S,11aβ)-Decahydro-4β-(2-propenyl)-1β,5β-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one 1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, decahydro-4-(2-propen-1-yl)-, (1S,4S,5S,11aR)-
|
CAS | 550-43-6
|
1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, decahydro-4-(2-propen-1-yl)-, (1S,4S,5S,11aR)- - Physico-chemical Properties
Molecular Formula | C14H22N2O
|
Molar Mass | 234.34 |
Density | 1.10±0.1 g/cm3(Predicted) |
Melting Point | 79-80 °C(Solv: ligroine (8032-32-4)) |
Boling Point | 377.6±31.0 °C(Predicted) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Off-White to Brown Oil to Low-Melting |
pKa | 10.07±0.40(Predicted) |
Storage Condition | Refrigerator |
1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, decahydro-4-(2-propen-1-yl)-, (1S,4S,5S,11aR)- - Introduction
angustifoline is an alkaloid that belongs to a class of acetylcholinesterase inhibitors. It is obtained from plants such as the chandodendron tomentosum. angustifoline is a colorless crystalline powder with a bitter taste.
angustifoline has some potential uses in the medical field. It is investigated for use as an anticholinesterase agent in the treatment of diseases related to the cholinergic system, such as Alzheimer's disease. In addition, it may also have pharmacological activities such as anti-inflammatory, anti-pain and antibacterial.
Methods for preparing angustifoline include extraction and synthesis from plants. Extraction of angustifoline from plants generally involves disruption of plant tissue, extraction and isolation using solvents. For the synthesis of angustifoline, a series of organic synthesis reactions are required to synthesize the target compound.
There is currently no sufficiently reliable data on the safety information of angustifoline. Before using angustifoline, more research should be conducted to understand its potential toxicological and pharmacokinetic properties, and to ensure that appropriate safety measures are taken during use. In addition, if any adverse reactions or allergic reactions occur, a doctor or professional should be consulted promptly.
Last Update:2024-04-09 21:54:55